Today's crossword puzzle clue is: Major highway through the southern U.S.. We'll attempt to find the correct answer for this specific clue. Below are the potential solutions for "Major highway through the southern U.S.". It was last seen in New York Times Crossword. Our database has 1 possible answer. Our latest answer ITEN (Nov 21 2024) for Major highway through the southern U.S. has a total of 4 letters.
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