ACETAMIDE

HOMEPLATERunner's goal, maybe DIOGOJOTAPortuguese international forward who died in a car crash in 2025 CHAINGANG1960 Sam Cooke single that was a top ten hit in both the US and the UK THEMIKADOGilbert and Sullivan comic opera subtitled The Town of Titipu EMPTYSUITNo-talent boss GODHELPMERequest for assistance from a higher-up? LOSESFACEGoes down in estimation LIGHTENUP"Just relax!" IMEANYEAH"Sure … that's true …" KITKATBAR"Break me off a piece" snack AROMANTICLike a person who might prefer platonic relationships TALKLIKEARead with 22-Across, September 19 observance whose celebrants might shout "Shiver me timbers!" PAINTWORKA colourful finish SMARTMOVE"That's good thinking"