BUFFEREDASPIRIN

TAKEITORLEAVEITYou shouldn't have holiday sex with wretched Keir to please yourself EDINBURGHTATTOOForces show terrible drug being cut: heroin put into skin with needle (9, 6) STRAIGHTSHOOTERTrue American siren chasing pure son (8,7) THEATRICALAGENTProfessional representative could be awful charlatan getting cut repeatedly: first 12.5% of earnings ROYALALBERTHALLLondon venue named after Queen Victoria's husband ONSPEAKINGTERMSQuite friendly person playing with mates, man paying a visit (2,8,5) GRILLEDEGGPLANTCharred vegetable often paired with tahini FIFTYFIRSTSTATELIST, say, how Trump sees Canada? (5-5,5) MARSHMALLOWPEEPEaster basket treat SOLARBRILLIANCEIntense sunlight HITSFORTHECYCLEGets a single, double, triple, and home run in one game AGAINSTTHEGRAINContrary to inclination, objecting to Scotch? (7,3,5) HELLORHIGHWATERAny foreseeable difficulty ... with a hint to 17-, 25-, 50- and 60-Across INTHEFIRSTPLACEPin left with shirt worried one initially