DEFIANT

IASKYOUA burden for a Titan in debt – Lord have mercy! (1,3,3) MRSLATEFred Flintstone's boss at the rock quarry ECUADORCountry in South America – road cue (anag) (7) SORCERYMagic CONFIRMProve bit of negligence in two companies SMOKINGFamily stopping small cat doing unhealthy activity MALAYAN__ bear: Southeast Asian forest dweller GREATERMore extensive ONAROLLExperiencing continuous streak of good luck (2,1,4) SIGNALSLeft and right turn indicators, e.g. BRANDONJason's "Beverly Hills, 90210" role ELLAGICRelating to acid derived from gall nuts put into melting ice JUGULARDescribing a vessel – whimsically or not? (7) EMOTIVEDelicate (7)