Crossword answer
ISME
4 letters · Used for 4 different clues · 8 appearances · Last seen Daily Themed, October 4, 2025
Letter pattern
ISME
Clues that lead to ISME
Most recent firstAbout ISME in crosswords
ISME is a 4-letter answer that has appeared 8 times in our database across 4 different clues. It was most recently the answer to “"Woe ___!" (sorrowful exclamation): 2 wds.” in the Daily Themed crossword on October 4, 2025.
Other 4-letter answers
VENTOrifice
TENSSawbucks
LEAKAir mattress annoyance
IOUS"Will settle up later" slips
FLATBuilding unit razed to the ground? (4)
REEDVibrating cane in oboe (4)
HOOT62-Across call
LIST"It's on my to-do ___" ("I haven't forgotten about that")
IDESMarch time
BOATContainer for gravy (4)
MAUI___ Wowie (cocktail with a rhyming name)
WASPWestern snake that stings rather than bites
UNITGroup
TEAMThunder or Lightning?
Every appearance of ISME (8)
Click to expand · newest first
Oct 4, 2025
"Woe ___!" (sorrowful exclamation): 2 wds. · Daily Themed · 51 Across
May 27, 2024
"Woe ___!": 2 wds. · Daily Themed · 8 Down
Feb 21, 2024
“Woe —!” · Eugene Sheffer · 31 Down
Dec 2, 2022
"Woe ___!": 2 wds. · Daily Themed · 22 Down
Oct 25, 2022
"Woe ___!": 2 wds. · Daily Themed · 28 Down
Dec 10, 2021
"This ___" (song from "The Greatest Showman"): 2 wds. · Daily Themed · 19 Across
Oct 8, 2021
"This ___," song from "The Greatest Showman": 2 wds. · Daily Themed · 15 Down
Jul 6, 2020
“Woe —!” · Eugene Sheffer · 29 Down