Crossword answer
LYME
4 letters · Used for 5 different clues · 6 appearances · Last seen New York Times, September 19, 2026
Letter pattern
LYME
Clues that lead to LYME
Most recent firstClueLettersPuzzleLast seen
Connecticut town that lent its name to a tick-borne disease4New York TimesSep 19, 2026
___ disease (tick-borne disease)4Daily ThemedJul 18, 2026
Old --, Connecticut4Eugene ShefferMay 5, 2026
Tick-borne affliction, informally4New York TimesSep 11, 2025
Old —, Connecticut4Eugene ShefferAug 28, 2023
About LYME in crosswords
LYME is a 4-letter answer that has appeared 6 times in our database across 5 different clues. It was most recently the answer to “Connecticut town that lent its name to a tick-borne disease” in the New York Times crossword on September 19, 2026.
Other 4-letter answers
HIREBring on board
TOONMickey or Minnie
EDAMCheese from the Netherlands
COMEAttend
ISEE"So that's how it is"
ABLEUp to the task
RAGSCleaning cloths
REEKStink
BONEChew toy shape, often
SAKSLuxury goods retailer since 1867
SEEDSunflower bit
EVERAlways highly regarded in red
DAFT____ Punk
SLOWSign in a construction zone
Every appearance of LYME (6)
Click to expand · newest first
Sep 19, 2026
Connecticut town that lent its name to a tick-borne disease · New York Times · 48 Down
Jul 18, 2026
___ disease (tick-borne disease) · Daily Themed · 2 Down
May 5, 2026
Old --, Connecticut · Eugene Sheffer · 11 Down
Sep 11, 2025
Tick-borne affliction, informally · New York Times · 33 Across
Aug 28, 2023
Old —, Connecticut · Eugene Sheffer · 17 Across
Jan 15, 2023
___ disease (tick-borne disease) · Daily Themed · 49 Down