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Wednesday, August 26, 2026
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Crossword answer

LYME

4 letters · Used for 4 different clues · 5 appearances · Last seen Daily Themed, July 18, 2026
Letter pattern
LYME
Starts with L, ends with E · 4 letters
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Clues that lead to LYME

Most recent first
ClueLettersPuzzleLast seen
___ disease (tick-borne disease)4Daily ThemedJul 18, 2026 Old --, Connecticut4Eugene ShefferMay 5, 2026 Tick-borne affliction, informally4New York TimesSep 11, 2025 Old —, Connecticut4Eugene ShefferAug 28, 2023

About LYME in crosswords

LYME is a 4-letter answer that has appeared 5 times in our database across 4 different clues. It was most recently the answer to “___ disease (tick-borne disease)” in the Daily Themed crossword on July 18, 2026.

Every appearance of LYME (5)

Click to expand · newest first
Jul 18, 2026
___ disease (tick-borne disease) · Daily Themed · 2 Down
May 5, 2026
Old --, Connecticut · Eugene Sheffer · 11 Down
Sep 11, 2025
Tick-borne affliction, informally · New York Times · 33 Across
Aug 28, 2023
Old —, Connecticut · Eugene Sheffer · 17 Across
Jan 15, 2023
___ disease (tick-borne disease) · Daily Themed · 49 Down